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How often should you use chloramphenicol? If you 're using 1% chloramphenicol eye ointment, apply it to the affected eye every 3 hours (during waking hours). Do this 3 to 4 times a day, or as your doctor advises. With more severe infections, your doctor may recommend using eye ointment at bedtime and eye drops during the day. Orville Gerald searches for chloromycetin
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